Carcinogenesis bioassay of chlorinated dibenzodioxins and related chemicals.

Sources and fate of polychlorinated dibenzodioxins, dibenzofurans and related compounds in human environments.

Several of the major incidents resulting in potential human exposures to polychlorinated dibenzodioxins (PCDDs) and/or polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and related compounds which have occurred in the U.S. in recent periods have resulted from improper disposal of hazardous chemical wastes. Prominent examples of such environmental contamination episodes are...

Recent findings on the carcinogenicity of chlorinated olefins.

Data are presented on factors affecting the carcinogenic effects of chlorinated olefins, such as molecular structure, concentration, length of treatment, route of administration and animal species, strain, sex, and age. The observations are based upon carcinogenicity experimental bioassays of vinyl chloride and vinylidene chloride. Early results, which appear to show that some of these factors ...

The U.S. federal framework for research on endocrine disruptors and an analysis of research programs supported during fiscal year 1996.

The potential health and ecological effects of endocrine disrupting chemicals has become a high visibility environmental issue. The 1990s have witnessed a growing concern, both on the part of the scientific community and the public, that environmental chemicals may be causing widespread effects in humans and in a variety of fish and wildlife species. This growing concern led the Committee on th...

Contamination of the Bay of Fundy—Gulf of Maine area with Polychlorinated Biphenyls, Polychlorinated Terphenyls, Chlorinated Dibenzodioxins, and Dibenzofurans

The procedure used to determine polychlorinated biphenyls (PCBs), polychlorinated terphenyls (PCTs), chlorinated dibenzodioxins, and chlorinated dibenzofurans is outlined in Table 1. It is based on the cleanup-chromatography of Holden and Marsden (1), modified as described (2). Most PCBs are eluted in fraction I. Fraction II contains some PCBs, p ,p'-DDE, and PCTs, whereas heptachlor exposide, ...

Determination of chlorinated dibenzo-p-dioxins and dibenzofurans in various materials.